The Significance of Combined Measurement of Three Kinds of Protein in Urine for Children with Renal Disease

In order to study the clinical value of combined measurement of Alb, IgG and β 2-MG in urine in early diagnosis and determining the involved area for children with renal disease,urinary Alb,IgG and β 2-MG were measured by radioimmunoassay in 131 children with renal disease.The results showed that the levels of Alb,IgG and β 2-MG in acute nephritis group and nephrotic syndrome group were significantly higher than those in the control group ( P 0.01);in nephrotic syndrome group,the level of β 2-MG was significantly higher than that in the control and nephritis group( P 0.01). So,combined measurement of Alb,IgG and β 2-MG in urine could be useful to reflect the renal damage in early stage and distinguish between glomerular and tubular damage.