2014•Gansu Medical JournalRequires access
Clinical effects and security analysis of combination of carvedilol and valsartan on patients with chronic heart failure
Bai Wen-lia
Open publisher page 0 citations
Abstract
Objective: To explore clinical effects and security analysis of combination of carvedilol and valsartan on patients with chronic heart failure. Methods: 118 patients with chronic heart failure patients in our hospital were divided randomly into observation group and control group according to the figure.The control group were taken valsartan and the observation group were taken carvedilol treatment on the basis of taking valsartan in which the clinical effect and security were compared in two groups. Results: The left ventricular end-systolic diameter,left ventricular end-diastolic diameter,left ventricular end-systolic capacity,left ventricular end-diastolic volume, left ventricular ejection fraction and stroke volume were better improved in the observation group than that in the control group in which the difference was statistically significant(P0.05). The total efficiency in observation group was 94.92%,the control group was 83.05% in which the difference was statistically significant(P0.05). There was no serious adverse drug reactions in the observation group and control group. Conclusion:Combination of carvedilol and valsartan on patients with chronic heart failure is a safe and reliable treatment.