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Effects of Danxian Kanggu Capsule on Proliferation and Differentiation of Cultured Osteoblasts in Vitro

Ri Liu

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Abstract

Objective :To investigate the effects of Danxian Kanggu(DXKG)capsule extracted from traditional Chinese medicine on cultured osteoblasts in vitro. Methods :MTT,PNPP and BGP content radioimmunoassay were used to observe the proliferation,the activity of ALP and the BGP content of osteoblasts cultured in vitro. Results :It was found that DXKG capsule had the effects on stimulating the proliferation,ALP activity and the BGP content of cultured osteoblasts in different concentration. Conclusion :DXKG capsule has effects on stimulating the proliferation and the differentiation,and increasing the activity of ALP and the BGP content of cultured osteoblasts in vitro.

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What this paper is about

Objective :To investigate the effects of Danxian Kanggu(DXKG)capsule extracted from traditional Chinese medicine on cultured osteoblasts in vitro. Methods :MTT,PNPP and BGP content radioimmunoassay were used to observe the proliferation,the activity of ALP and the BGP content of osteoblasts cultured in vitro. Results :It was found that DXKG capsule had the effects on stimulating the proliferation,ALP activity and the BGP content of cultured osteoblasts in different concentration. Conclusion :DXKG capsule has effects on stimulating the proliferation and the differentiation,and increasing the activity of ALP and the BGP content of cultured osteoblasts in vitro.

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Available abstract

Objective :To investigate the effects of Danxian Kanggu(DXKG)capsule extracted from traditional Chinese medicine on cultured osteoblasts in vitro. Methods :MTT,PNPP and BGP content radioimmunoassay were used to observe the proliferation,the activity of ALP and the BGP content of osteoblasts cultured in vitro. Results :It was found that DXKG capsule had the effects on stimulating the proliferation,ALP activity and the BGP content of cultured osteoblasts in different concentration. Conclusion :DXKG capsule has effects on stimulating the proliferation and the differentiation,and increasing the activity of ALP and the BGP content of cultured osteoblasts in vitro.

Key concepts: In vitro, Capsule, Medicine, Osteoblast, Radioimmunoassay, Internal medicine, Endocrinology, Cell biology

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