Study on the changes of serum levels of CRP and there clinical correlation in patients with acute cerebral Infarction

Objective To explore the role of CRP in the pathogenesis of acute cerebral infarction.Methods The study group included 50 patients with acute cerebral infarction and 30 healthy people as control group.Serum CRP was measured by enzyme-linked immunosorbent assay(ELISA)respectively at 1,3,7,14 days.Results Compared with control group,the serum levels of CRP at 1,3,7,14 days in patients with acute cerebral infarction were increased significantly(P0.05),the levels at 3 days were the highest in patients with acute cerebral infarction.There was a positive correlation between the increasing degree of serum levels of CRP and the size of infarct area(P0.05).Conclusion Serum CRP was increased significantly in patientswith acute cerebral infarction,which possibly played a key role in the pathogenesis of acute cerebral infarction,therefore anti-inflammatory drugs maybe will become potential new therapeutic agents for acute cerebral infarction.