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Candida nosocodial infections in Tumor chemotherapy patients

Xiaoyan Wu

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Abstract

Objective:To study the distribution of Candida infection and drug resistance in tumor chemotherapy patients and provide evidence for the clinical use of antifungal agents.Methods: Using ID 32C provided by the French company bioMerieux to identify Candida,according to CLSI requirements,antifungal susceptibility testing of Candida was performed by ATBTM FUNGUS Fungal Susceptibility strips.Results: There were five major species causing candida infection,of which C.albicans was the most,accounting for 55.3%;followed by C.tropicalis(13.0%),C.glabrata(12.6 %),C.parapsilosis(8.9 %),C.krusei(4.8 %).The resistance to antifungal drug of piromidic was common,resistance to 5-FC(17.3%)second,resistance to AMB(2.5%)less.Conclusion: Candida infection is caused by Candida albicans mainly;Candida is present antifungal drug resistance in general,sufficient amount of medication should be combined.

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Objective:To study the distribution of Candida infection and drug resistance in tumor chemotherapy patients and provide evidence for the clinical use of antifungal agents.Methods: Using ID 32C provided by the French company bioMerieux to identify Candida,according to CLSI requirements,antifungal susceptibility testing of Candida was performed by ATBTM FUNGUS Fungal Susceptibility strips.Results: There were five major species causing candida infection,of which C.albicans was the most,accounting for 55.3%;followed by C.tropicalis(13.0%),C.glabrata(12.6 %),C.parapsilosis(8.9 %),C.krusei(4.8 %).The resistance to antifungal drug of piromidic was common,resistance to 5-FC(17.3%)second,resistance to AMB(2.5%)less.Conclusion: Candida infection is caused by Candida albicans mainly;Candida is present antifungal drug resistance in general,sufficient amount of medication should be combined.

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Available abstract

Objective:To study the distribution of Candida infection and drug resistance in tumor chemotherapy patients and provide evidence for the clinical use of antifungal agents.Methods: Using ID 32C provided by the French company bioMerieux to identify Candida,according to CLSI requirements,antifungal susceptibility testing of Candida was performed by ATBTM FUNGUS Fungal Susceptibility strips.Results: There were five major species causing candida infection,of which C.albicans was the most,accounting for 55.3%;followed by C.tropicalis(13.0%),C.glabrata(12.6 %),C.parapsilosis(8.9 %),C.krusei(4.8 %).The resistance to antifungal drug of piromidic was common,resistance to 5-FC(17.3%)second,resistance to AMB(2.5%)less.Conclusion: Candida infection is caused by Candida albicans mainly;Candida is present antifungal drug resistance in general,sufficient amount of medication should be combined.

Key concepts: Candida krusei, Candida glabrata, Candida albicans, Candida tropicalis, Candida parapsilosis, Microbiology, Drug resistance, Antifungal

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