2009•Journal of Binzhou Medical UniversityRequires access
The difference of serum leptin in different types of hepatic cirrhosis patients
Zheng Tie-long
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Abstract
Objective To study the difference of serum leptin in different types of hepatic cirrhosis patients.Methods Detect the serum leptin of the patients through radioimmunity,and compare the difference of serum leptin in different types of hepatic cirrhosis patients.Results The serum leptin in all types of hepatic cirrhosis was obviously higher than that in normal control(P0.01).There was no significant difference between the serum leptin in hepatitis B cirrhosis and hepatitis C cirrhosis patients(P0.05).There was no significant difference between the serum leptin in alcoholic hepatic cirrhosis and non-alcoholic fatty cirrhosis patients(P0.05).The serum leptin in alcoholic cirrhosis and non-alcoholic fatty hepatic cirrhosis patients was obviously higher than that in hepatitis B cirrhosis and hepatitis C cirrhosis patients(P0.05).Conclusion The serum leptin in cirrhosis patients increased obviously.The serum leptin in alcoholic hepatic cirrhosis and non-alcoholic fatty hepatic cirrhosis patients increased more obviously because of the activation of HSC and the leptin resistance.