2003•Chinese Journal of Clinical HepatologyRequires access
Measuring the level of serum lepin in chronic liver disease.
Piao Yun
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Abstract
To determine the possible clinical significance of the serum leptin through estimating its levels in chronic hepatitis, fatty liver and cirrhosis of liver. 21 patients with fatty liver, 21 patients with cirrhosis of liver and 21 normal persons were admitted to the investigations: the height and weight of the candidates were measured simultaneously, body mass index and percent of body fat were calculated. The level of leptin was measured by ELISA. We found that the level of leptin from hepatitis and fatty liver is significantly higher than that of the control; there is no difference between the cirrhosis of liver and the control and no difference between male and female in cirrhosis of liver, no difference was found between the level of leptin and the stratification of the liver function. The level of leptin from hepatitis C is not related to that of the control. Leptin is related to a lot of chronic hepatitis.