2009•Chinese Journal of Laboratory DiagnosisRequires access

Quercetin on the effect of colon cancer cell line Lovo in vitro

Han Xue-me

Abstract

Objective To investigate the effect of Quercetin on the proliferation and apoptosis of the colon carcinoma cell line Lovo.Methods The cultured Lovo cells were treated with different concentrations of Quercetin for different time.The proliferation of Lovo cells was detected by MTT method.Cell apoptosis and cell circle were detected by flow cytometry.Results Quercetin inhibited the proliferation of Lovo cells in a concentration-and time dependent manner.Quercetininduced the apoptosis and inhibted the cell circle of Lovo cells in a concentration-dependent manner.Conclusion Quercetin can induce the apoptosis of the colon carcinoma cell line Lovo,reduce the proliferation of Bcl-2,and inhibite the cell circle of colon carcinoma.

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Apoptosis, Flow cytometry, Cell growth, Cell culture, Quercetin, Cell, In vitro, MTT assay