Effect of vinpocetine in acute cerebral infarction:on 40 cases report

Objective To observe the effect of vinpocetine on acute cerebral infarction(ACI).Methods 80 patients with ACI were randomly divided into treatment group and control group,each of 40 cases.Control group were given usual treatment,treatment group were given 20 mg vinpocetine,once daily.Clinical outcomes were taken in all patients 14 days after treatment.Blood test were taken before and 14 days after the treatment.Results After the treatment,the total effective rate in treatment group was 95.0% higher than 75.0% in control group(P0.05).There was no significant difference in hemorheological parameters of two groups before treatment(P0.05).After treatment,the whole blood viscosity,plasma viscosity,erythrocyte aggregation,fibrinogen and platelet aggregation rate levels were lower than those before the treatment of two groups(P0.05 or P0.01),and treatment group were lower than control group(P0.05).Conclusion Vinpocetine is a brain protective agent,which is very safe and effective and can be popularized.