Curative effects of edaravone combined with vinpocetine in treating acute cerebral infarction

Objective To observe the curative effects of edaravone combined with vinpocetine in treating acute cerebral infarction(ACI).Method Total 70 patients with ACI were randomly divided into two groups.The united treatment group(n=35) was treated with edaravone(30 mg iv drip,bid,for 14 days),and vinpocetine(20 mg iv drip,bid,for 14 days).The control group(n=35) was treated with vinpocetine only,whose usage was the same as that of the united treatment group.Neurological deficit scores,blood clotting index,liver and renal function were examined before and after treatment in both groups.Results The total effective rate of the united treatment group(94.29%) was obviously higher than that in the control group(82.86%)(P0.05).Slight abnormal renal function occurred in one patient of the united treatment group,who recovered after stopping that medication.Conclusion Edaravone combined with vinpocetine can notably improve the symptom of ACI patients.