The diagnostic and prognostic value of the combined measurements of cTnI,CRP and BNP in patients with ischemic heart failure

Objective To explore the diagnostic and prognostic values of combined measurements of cardiac troponin I( cTnI),C reactive protein( CRP) and B-type natriuretic peptide( BNP) in patients with ischemia heart failure.Methods The serum cTnI,CRP and blood plasma BNP in 98 cases ischemic heart failure patients with different cardiac function classification and 95 coronary heart disease without heart failure patients,and a follow-up observation of the recurrence of recent cardiac events was performed.Results The levels of serum cTnI,CRP and blood plasma BNP between heart failure patients with different cardiac function grading and the control group were compared,and the differences were statistically significant.The worse the heart function was,the higher the concentration was( P 0.05).Serum cTnI,CRP and plasma BNP concentrations at hospital discharge in the cardiac events group were markedly higher than those in the non-cardiac events group( P 0.05).Conclusion Serum cTnI,CRP and plasma BNP concentrations in patients with congestive heart failure obviously increase,and the combined measurements of three indexes have important significance in clinical diagnosis and prognostic evaluation for heart failure.