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Effects of Shengwujian Oral Liquid on Immune Function in Mice

Lin Ni

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Abstract

Objective:To investigate effects of Shengwujian Oral Liquid on humoral immunity, cellular immunity, red blood cell (RBC) immunity and macrophage-phagocyte system (MPS).Methods:To observe the effects of Shengwujian Oral Liquid on serum IgG and complement C 3 content, white blood cell (WBC) count, RBC immune adhering function, 2,4-dinitrofluorobenzene (DNFB) induced-delayed type hypersensitivity (DTH) and phagocytic ability of macrophage in either normal mice or cyclophosphamide (CY)-induced-immunosuppressed mice.Results:Serum IgG and complement C 3 contents were increased in normal and/or CY-induced-immunosuppressed mice (P0.05～0.01); CY-induced-leucopenia was improved (P0.01); RBC immune adhering function was enhanced (P0.01); phagocytosis of macrophage was elevated (P0.01); DNFB induced-DTH was potentiated (P0.01).Conclusions:Shengwujian Oral Liquid possesses a similar ability of a biological response modifier as levamisole.

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What this paper is about

Objective:To investigate effects of Shengwujian Oral Liquid on humoral immunity, cellular immunity, red blood cell (RBC) immunity and macrophage-phagocyte system (MPS).Methods:To observe the effects of Shengwujian Oral Liquid on serum IgG and complement C 3 content, white blood cell (WBC) count, RBC immune adhering function, 2,4-dinitrofluorobenzene (DNFB) induced-delayed type hypersensitivity (DTH) and phagocytic ability of macrophage in either normal mice or cyclophosphamide (CY)-induced-immunosuppressed mice.Results:Serum IgG and complement C 3 contents were increased in normal and/or CY-induced-immunosuppressed mice (P0.05～0.01); CY-induced-leucopenia was improved (P0.01); RBC immune adhering function was enhanced (P0.01); phagocytosis of macrophage was elevated (P0.01); DNFB induced-DTH was potentiated (P0.01).Conclusions:Shengwujian Oral Liquid possesses a similar ability of a biological response modifier as levamisole.

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Available abstract

Objective:To investigate effects of Shengwujian Oral Liquid on humoral immunity, cellular immunity, red blood cell (RBC) immunity and macrophage-phagocyte system (MPS).Methods:To observe the effects of Shengwujian Oral Liquid on serum IgG and complement C 3 content, white blood cell (WBC) count, RBC immune adhering function, 2,4-dinitrofluorobenzene (DNFB) induced-delayed type hypersensitivity (DTH) and phagocytic ability of macrophage in either normal mice or cyclophosphamide (CY)-induced-immunosuppressed mice.Results:Serum IgG and complement C 3 contents were increased in normal and/or CY-induced-immunosuppressed mice (P0.05～0.01); CY-induced-leucopenia was improved (P0.01); RBC immune adhering function was enhanced (P0.01); phagocytosis of macrophage was elevated (P0.01); DNFB induced-DTH was potentiated (P0.01).Conclusions:Shengwujian Oral Liquid possesses a similar ability of a biological response modifier as levamisole.

Key concepts: Immune system, Levamisole, Immunology, Macrophage, Phagocytosis, Immunity, Phagocyte, Delayed hypersensitivity

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