2005•Zhongguo yixue wulixue zazhiRequires access

Effects of Effects of Leonurus Heterophyllus Solution on Hemorheology and Blood Flow Volume of Organs in Rats with Heamoregic Shock

DU Shu-ting

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Abstract

Objective: To explore effects of Leonurus heterophyllus solution(LHS)on hemodynamic.s in rats with heamoregic shock. Methods: A model of heamoregic shock was made by blood loss from carotid in rats, and the regulative effect of LHS on hemodynamics was observed in rats with heamoregic shock by an observation of mesenteric microcirculation and determination of hemorheology and blood flow volume. Results: The micro-blood flow volume of organs was reduced and blood viscosity increased during heamoregic shock. The micro-area blood flow volume of stomach, intestine and liver was evidently increased in AHL and NS group, however, the former effect was superior to the NS group (p 0.05). After treatment of LHS, the blood viscosity and palelet aggregation were obviously lower than that of NS group, and meantime the deformity ability of RBC was obviously increased (p 0.05). Conclusion: LHS can obviously the abnormity of hemody namics in rats with heamoregic shock.

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Objective: To explore effects of Leonurus heterophyllus solution(LHS)on hemodynamic.s in rats with heamoregic shock. Methods: A model of heamoregic shock was made by blood loss from carotid in rats, and the regulative effect of LHS on hemodynamics was observed in rats with heamoregic shock by an observation of mesenteric microcirculation and determination of hemorheology and blood flow volume. Results: The micro-blood flow volume of organs was reduced and blood viscosity increased during heamoregic shock. The micro-area blood flow volume of stomach, intestine and liver was evidently increased in AHL and NS group, however, the former effect was superior to the NS group (p 0.05). After treatment of LHS, the blood viscosity and palelet aggregation were obviously lower than that of NS group, and meantime the deformity ability of RBC was obviously increased (p 0.05). Conclusion: LHS can obviously the abnormity of hemody namics in rats with heamoregic shock.

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Available abstract

Objective: To explore effects of Leonurus heterophyllus solution(LHS)on hemodynamic.s in rats with heamoregic shock. Methods: A model of heamoregic shock was made by blood loss from carotid in rats, and the regulative effect of LHS on hemodynamics was observed in rats with heamoregic shock by an observation of mesenteric microcirculation and determination of hemorheology and blood flow volume. Results: The micro-blood flow volume of organs was reduced and blood viscosity increased during heamoregic shock. The micro-area blood flow volume of stomach, intestine and liver was evidently increased in AHL and NS group, however, the former effect was superior to the NS group (p 0.05). After treatment of LHS, the blood viscosity and palelet aggregation were obviously lower than that of NS group, and meantime the deformity ability of RBC was obviously increased (p 0.05). Conclusion: LHS can obviously the abnormity of hemody namics in rats with heamoregic shock.

Key concepts: Hemorheology, Shock (circulatory), Hemodynamics, Blood flow, Microcirculation, Erythrocyte aggregation, Blood viscosity, Blood volume

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