Efficacy observation of exogenous pulmonary surfactant in treatment of neonatal meconium aspiration syndrome

Objective To investigate the effect of exogenous pulmonary surfactant(PS) in the treatment of neonatal meconium aspiration syndrome(MAS).Methods 40 cases of patients with MAS admitted in NICU were randomly divided into treatment group and control group,the same method of comprehensive treatment was used to two groups,while exogenous PS was used to the treatment group based on the control group.Results In the observation group,duration of mechanical ventilation,oxygen exposure time and hospital stay was lower than that of the control group,there was significant difference(P0.05). The incidence of death,gas leakage,sepsis,ventilator associated pneumonia in the observation group was significantly reduced compared with the control group,there was significant difference(P0.05).Conclusion The therapeutic effect of exogenous PS treatment of MAS is significant,and can reduce the mortality rate and complications of patients,relieve the clinical symptoms,be worthy of clinicians use.