Observation of curative effect on Losartan Potassium and Hydrochlorothiazide in the treatment of senile hypertension

Objective To observe the curative effect of Losartan Potassium and Hydrochlorothiazide in the treatment of senile hypertension.Methods One hundred and twenty elderly patients with essential hypertension were given Losartan Potassium and Hydrochlorothiazide(Losartan Potassium 50 mg,Hydrochlorothiazide 12.5 mg) one pill,once a day,morning intake,once a day,they were observed for two weeks and followed up for a month;the blood pressure,blood glucose,blood lipids,blood uric acid,potassium,liver and kidney function and adverse reactions during the treatment were observed.Results After taking Losartan Potassium and Hydrochlorothiazide for one week,the systolic blood pressure and diastolic blood pressure began to decrease and there was statistically significant difference of the blood pressure before and after treatment(P 0.05).Among the patients with hypertension of grade one and two,the patients with high-sodium diet had the most obvious effects and had no significant adverse reactions.Conclusion Losartan Potassium and Hydrochlorothiazide has an exact curative effect,which can reduce hypertension of elderly patients smoothly,and it is of high security,easy to take,and with good compliance and fewer adverse reactions.