2011•Journal of clinical and experimental medicineRequires access

The evaluation of Hyzaar in treatment of elderly patients with hypertension

Rao Li-fen

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Abstract

Objective To study the clinical efficacy of Hyzaar in treatment of senile hypertension.Methods One hundred cases of elderly hypertension were treated with Hyzaar(losartan potassium 50 mg and hydrochlorothiazide 12.5 mg),l tablet every morning for 6 weeks,and regular examination of blood pressure was taken during the treatment course,and changes in blood pressure,heart rate and adverse reactions were closely observed.Results After two weeks of treatment with oral administration of Hyzaar,systolic pressure and diastolic blood pressure began to drop significantly,and the difference was statistically significant(P0.05).The antihypertensive effect after treatment for 6 weeks was most obvious,the total efficacy rate was 77.0 %,and no significant adverse reaction had been observed.Conclusion The effectiveness of Hyzaar is exact,and it can reduce high blood pressure in elderly patients with hypertension,its effect is stable,safe,with less adverse reactions,and it is worthy to be recommended for further application.

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Objective To study the clinical efficacy of Hyzaar in treatment of senile hypertension.Methods One hundred cases of elderly hypertension were treated with Hyzaar(losartan potassium 50 mg and hydrochlorothiazide 12.5 mg),l tablet every morning for 6 weeks,and regular examination of blood pressure was taken during the treatment course,and changes in blood pressure,heart rate and adverse reactions were closely observed.Results After two weeks of treatment with oral administration of Hyzaar,systolic pressure and diastolic blood pressure began to drop significantly,and the difference was statistically significant(P0.05).The antihypertensive effect after treatment for 6 weeks was most obvious,the total efficacy rate was 77.0 %,and no significant adverse reaction had been observed.Conclusion The effectiveness of Hyzaar is exact,and it can reduce high blood pressure in elderly patients with hypertension,its effect is stable,safe,with less adverse reactions,and it is worthy to be recommended for further application.

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Available abstract

Objective To study the clinical efficacy of Hyzaar in treatment of senile hypertension.Methods One hundred cases of elderly hypertension were treated with Hyzaar(losartan potassium 50 mg and hydrochlorothiazide 12.5 mg),l tablet every morning for 6 weeks,and regular examination of blood pressure was taken during the treatment course,and changes in blood pressure,heart rate and adverse reactions were closely observed.Results After two weeks of treatment with oral administration of Hyzaar,systolic pressure and diastolic blood pressure began to drop significantly,and the difference was statistically significant(P0.05).The antihypertensive effect after treatment for 6 weeks was most obvious,the total efficacy rate was 77.0 %,and no significant adverse reaction had been observed.Conclusion The effectiveness of Hyzaar is exact,and it can reduce high blood pressure in elderly patients with hypertension,its effect is stable,safe,with less adverse reactions,and it is worthy to be recommended for further application.

Key concepts: Medicine, Hydrochlorothiazide, Blood pressure, Adverse effect, Morning, Heart rate, Losartan, Internal medicine

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