Study on extraction process of Jizhi Pingchuan soft capsule

Objective To optimize the extraction process of Jizhi Pingchuan soft capsule. Methods Using baicalin and its homologous compounds and total extract contents as indexes,water-extraction and ethanol-extraction processes were screened. Choosing the amount of solvent added,the extracting time,and the extracting frequencies as investigation targets,the test was designed according to L9( 34) of orthogonal test and taking baicalin as the index to optimize the process parameters. Results With 70% ethanol as a extraction solvent can extract the effective components more fully. Orthogonal test indicated that the best condition of the extraction process was as follows: 12 times of 70% ethanol,extracting two times and every time 2 hours. Conclusions It is derived from screening that the process is stable,simple and repeatable,and suitable for the production amplification,and provide the possibility to future industrial applications.