Studies on the Technique of the Alcoholic Extraction of Ganzhixiao Capsule

Objective To optimize the alcoholic extraction technique of ganzhixiao capsule. Methods The total contents of anthraquinone from ganzhixiao capsules were regarded as the indicator,and L9(34) orthogonal study was applied to observe the concentration and amount of alcohol,extracting time and times of extraction in order to determine the best extracting technique. Results The times of extraction and the concentration of alcohol were the most significant factors,and the optimal extraction process required 70% alcohol,7 times amount of solvent,3 times extraction,2 h for each. Conclusion The results show that the extraction technique was stable,reliable and eligible for manufacturing instruments.