Optimization of the extraction technique of Pingchuan Cataplasm

Objective To optimize the extraction technique of Pingchuan Cataplasm.Methods An orthogonal test method of L9(34) was used to investigate the extraction time,solvent volume,the concentration of alcohol and backflow extract times,the extraction rate of sinapine thiocyanate was considered as the evaluation index to optimize the extraction technique.Results The optimized extraction technique were as follows: the medicinal material was extracted for 2 times with sixfold amount of 70% alcohol,2 hours per time.Conclusion The optimized technique is reasonable which can provide a good basis for the continuing research of transdermal absorption of this compound prescription.