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Correlation between Expression of HER-2 and Expression of Receptors of Estrogen and Progestogen in the Breast Cancer and Its Significance

Jiang Yu

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Abstract

Objective:To explore the clinical significance and expression of HER-2,ER and PR in breast cancer tissue.Methods:The expression of HER-2,ER and PR in breast cancer tissues were measured by immunohistochemistry in 167 cases of breast cancers.Results:The positive rates of expression of HER-2,ER and PR in the breast cancers reached 44.9%、53.3% and 49.1%,respectively.The positive rate of expression of HER-2 in the cauces group with the expression of ER,PR was lower than that in the negative group(P0.0 5).The positive rate of expression of HER-2 in the group with the lymph node metastasis was higher than that in non-lymph node metastasis group(P0.05).Conclusion:Measurement of HER-2,ER and PR in the breast cancers played an important role in the prognostic evaluation and guiding of clinical treatment.

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What this paper is about

Objective:To explore the clinical significance and expression of HER-2,ER and PR in breast cancer tissue.Methods:The expression of HER-2,ER and PR in breast cancer tissues were measured by immunohistochemistry in 167 cases of breast cancers.Results:The positive rates of expression of HER-2,ER and PR in the breast cancers reached 44.9%、53.3% and 49.1%,respectively.The positive rate of expression of HER-2 in the cauces group with the expression of ER,PR was lower than that in the negative group(P0.0 5).The positive rate of expression of HER-2 in the group with the lymph node metastasis was higher than that in non-lymph node metastasis group(P0.05).Conclusion:Measurement of HER-2,ER and PR in the breast cancers played an important role in the prognostic evaluation and guiding of clinical treatment.

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Available abstract

Objective:To explore the clinical significance and expression of HER-2,ER and PR in breast cancer tissue.Methods:The expression of HER-2,ER and PR in breast cancer tissues were measured by immunohistochemistry in 167 cases of breast cancers.Results:The positive rates of expression of HER-2,ER and PR in the breast cancers reached 44.9%、53.3% and 49.1%,respectively.The positive rate of expression of HER-2 in the cauces group with the expression of ER,PR was lower than that in the negative group(P0.0 5).The positive rate of expression of HER-2 in the group with the lymph node metastasis was higher than that in non-lymph node metastasis group(P0.05).Conclusion:Measurement of HER-2,ER and PR in the breast cancers played an important role in the prognostic evaluation and guiding of clinical treatment.

Key concepts: Medicine, Progestogen, Breast cancer, Immunohistochemistry, Estrogen receptor, Oncology, Internal medicine, Cancer

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Correlation between Expression of HER-2 and Expression of Receptors of Estrogen and Progestogen in the Breast Cancer and Its Significance — Research Paper | ScholarLens