Clinical Observation of Mifepristone and Misoprostol with Murray Rivanol Used in Mid-pregnancy Induction of 89 Cases

Objective To study the clinical effects of mid-pregnancy' termination with mifepristone,misoprostol and murray rivanol.Methods 89 pregnant voluntary women to terminate pregnancy(12 to 28 weeks pregnant)were randomly divided into the observation group and the treatment group.The observer Group used mifepristone,dose was 75 mg,at the same time,100mg murray rivanol amniotic injected,after 24 hours,400μg misoprostol fushed into vaginal.The control group used the conventional method,100mg murray rivanol amniotic injected.After the baby is delivered,the conventional intramuscular or intravenous oxytocin 20U,given antibiotics to prevent infection.Results The success rates of two group were 100%,the difference was not significant(P0.05).The average total time of induction,the observe group was 28.90h,and the control group was 56.15h,between the two groups there was a significant difference(P0.05);The average time of 2h postpartum bleeding,the observe group was 104.99 mL,the control group was 167.80ml,there was a significant difference(P0.05)between the two groups.Conclusion Termination of mid-pregnancy by mifepristone,misoprostol with Li-fan connaught can reduce labor and reduce the suffering of pregnant women,reduce bleeding and less adverse reaction,it is a safe and effective method of induction in clinical.