Induction of Labor in Mid-pregnant Used Mifepristone Combined With Misoprostol

Objective To discuss the effect of the method with vaginal misoprostol placed after mifepristone took orally for induction of labor patients in mid-pregnant.Methods From October,2008 to October,2010,totally 120 pregnants between 14-26 weeks were selected to study,and randomly divided into two groups,one for observation,the other is for comparison.Cases in observation group took 150 mg mifepristone orally and placed misoprostol 0.4 mg the next day;cases in comparison group injected intra-amniotic with rivanol 100 mg.Results Between two groups,the significant difference exsisted in induction time and incomplete abortion rate(P0.05),but there was no significant difference in the amount of bleeding,side effects such as nausea,vomiting etc.Conclusion Drugs induction is better than amniocentesis abortion with rivanol,mifepristone combined with misoprostol abortion is a safe and effective method,which is better than rivanol intra-amniotic injection.