Effect of Gankang IV on SOD and MDA of Liver Tissue in Rats with Fatty Liver

Objective To explore the effect of LPO-resistance with Gankang IV(GKIV) on fatty liver to provide the experimental basis for the clinical therapy of fatty liver.Methods:64 wistar rats were divided randomly into six group.The animal model of fatty liver was duplicated with high fat diet and alcohol.All the treatment groups were intervened by its own medicine,Gankang IV(GKIV)and DongBao GanTai(DBGT).After 8 weeks,all animals were killed to take the blood 2ml and check the liver function immediately.Live tissue in animal was extracted to be made into the 10% hepatic tissue fluid,tested the SOD and MDA.Results:The AST and ALT contents in serum decreased significantly and The SOD/MDA contents in hepatic tissue increased/decreased significantly in GKIV group than that of model group and DBGT group(P0.05).Conclusion:GKIV can promote the LPO-resistance competence of liver and prevent fatty liver developing.