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2011•China Modern MedicineRequires access

Clinical efficacy of doxofylline and aminophylline in treating acute exacerbation chronic obstructive pulmonary disease

Cai Ming-wen

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Abstract

Objective: To compare the clinical efficacy of doxofylline and aminophylline in treating acute exacerbation chronic obstructive pulmonary disease (AECOPD). Methods: 78 patients of AECOPD were randomly divided into study group and control group. Besides from conventional therapy, the patients of the study group were treated with doxofylline 300 mg, while the control group were treated with aminophylline 250 mg once a day, the clinical efficacy were compared after 7 days. Results: After treatment, the clinical symptoms of the study group improved significantly better than the control group (P0.05), there was a significant difference on lung function in two groups ( P0.05). Conclusion: The clinical efficacy to improve lung function of doxofylline is superior to aminophylline in treating AECOPD, should be widely applied.

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What this paper is about

Objective: To compare the clinical efficacy of doxofylline and aminophylline in treating acute exacerbation chronic obstructive pulmonary disease (AECOPD). Methods: 78 patients of AECOPD were randomly divided into study group and control group. Besides from conventional therapy, the patients of the study group were treated with doxofylline 300 mg, while the control group were treated with aminophylline 250 mg once a day, the clinical efficacy were compared after 7 days. Results: After treatment, the clinical symptoms of the study group improved significantly better than the control group (P0.05), there was a significant difference on lung function in two groups ( P0.05). Conclusion: The clinical efficacy to improve lung function of doxofylline is superior to aminophylline in treating AECOPD, should be widely applied.

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Available abstract

Objective: To compare the clinical efficacy of doxofylline and aminophylline in treating acute exacerbation chronic obstructive pulmonary disease (AECOPD). Methods: 78 patients of AECOPD were randomly divided into study group and control group. Besides from conventional therapy, the patients of the study group were treated with doxofylline 300 mg, while the control group were treated with aminophylline 250 mg once a day, the clinical efficacy were compared after 7 days. Results: After treatment, the clinical symptoms of the study group improved significantly better than the control group (P0.05), there was a significant difference on lung function in two groups ( P0.05). Conclusion: The clinical efficacy to improve lung function of doxofylline is superior to aminophylline in treating AECOPD, should be widely applied.

Key concepts: Medicine, Aminophylline, Exacerbation, Clinical efficacy, Acute exacerbation of chronic obstructive pulmonary disease, Pulmonary disease, Pulmonary function testing, Lung function

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