Clinical analysis of non-invasive positive pressure ventilation in the treatment of severe acute exacerbation of chronic obstructive pulmonary disease(AECOPD)with type II respiratory failure

Objective To study the clinical effect of non-invasive positive airway ventilation in the treament of severe COPD at acute exacerbation with type Ⅱ respiratory failure.Methods Fifty inpatients with sever AECOPD and type Ⅱ respiratory failure were divided into the treating group(n=23) and the control group(n=27) randomly during January 2008 to August 2009.Patients in both two groups were treated with oxygen therapy,antibiotics,methyl prednisolone as routine treatment.The non-invasive positive airway ventilation was used in the treating group.Heart rate,respiratory frequency,and arterial blood gases were detected before and after 72 hours treatment.Results There were considerable improvements in the arterial blood gases in the treating group after treatment compared with the controls.Conclusion Non-invasive positive pressure ventilation can be of great benefit to patients suffering from AECOPD and type Ⅱ respiratory failure.