Comparison on Efficacy in Treating Liver Fibrosis between Qinghao Biejia Decoction and Dahuang Zhechong Pill

To observe the efficacy of Qinghao Biejia Decoction of the famous prescription of seasonal febrile diseases in treating liver fibrosis of chronic hepatitis B, to seek the effective prescription against liver fibrosis. Methods: 143 liver fibrosis of chronic hepatitis B patients were randomly divided into group A and B. 75 patients in group A received Qinghao Biejia Decoction and 68 patients in group B received Dahuang Zhechong Pill for same weeks. The effects were observed on the change of hyaluronic acid (HA), pro-collagen Ⅲ (PCⅢ)、laminin (LN) and Ⅳ collagen ( Ⅳ-C). Results: Levels of serum HA, PC Ⅲ , LN. Ⅳ-C in the group A declined more obviously than that of group B, the defference was significant (P0. 01). In determination of treatment bsaed on the differentiation of symptoms and signs of traditional Chinese medicine, the obvious efficiency were observed for all kinds of syndromes in treating liver fibrosis (P0. 01). The control group was observed for syndrome of stagnation of Qi and blood stasis. Conclusion: Qinghao Biejia Decoction and differentiation of symptoms and signs are more effective than Dahuang Zhechong Pill in treating liver fibrosis. It is a good treating method against liver fibrosis.