Clinical efficacy and safety study of Moxifloxacin in the treatment of elderly patients with lower respiratory tract infection

Objective To study the clinical efficacy and safety of Moxifloxacin in the treatment of elderly patients with lower respiratory tract infection.Methods 86 cases of elderly patients with lower respiratory tract infection were randomly divided into the observation group and the control group,with 43 cases in each group,the observation group was given Moxifloxacin Injection 400 mg/d intravenous infusion therapy,the control group was given Levofloxacin Injection 400 mg/d intravenous infusion therapy.The clinical efficacy of the two groups,the rate of bacterial clearance,symptoms subsided time and adverse reactions were observed,and the contrast analysis was carried on.Results In the observation group,the total effective rate was 95.35%,significantly higher than 79.07% of control group(P 0.05);the observation group total bacterial clearance rate was 93.55%,significantly higher than 68.75% of control group(P 0.05);fever,cough,expectoration of observation group and pulmonary rales and other symptoms subsided time were significantly lower than those of control group(P 0.05);two groups of adverse reactions were mild,and the occurrence rate was no significant different(P 0.05).Conclusion Moxifloxacin in the treatment of lower respiratory tract infection in elderly patients has good curative effect,quick effect,antibacterial spectrum,lasting and many other advantages,and the adverse reactions are mild,it can be presented as clinical treatment of elderly patients with lower respiratory tract infection of a first drug.