Clinical evaluation of moxifloxacin in the treatment of lower respiratory tract bacterial infection in elderly patients

Objective To evaluate the efficacy and safety of moxifloxacin in the treatment of lower respiratory tract infection in elderly patients.MethodEighty-two elderly patients with lower respiratory tract bacterial infections were randomly divided into two groups.The treatment group(n=42) was given 400 mg of moxifloxacin intravenously,once daily for seven days,and the control group(n=40) was given levofloxacin 400 mg intravenously,once daily for seven days.ResultsThe clinical effective rates of the treatment group and the control group were 95.2% and 90.0%,respectively,there was no significant difference between the two groups(P0.05);The bacterial clearance rates of the two groups were 93.3 % and 72.4%,respectively,the difference between the two groups had statistical significance(P0.05);The adverse reaction rates of the treatment group and the control group were 7.1% and 10.0%,respectively.Conclusion Moxifloxacin is an effective and safe antibacterial drug in the treatment of lower respiratory tract bacterial infections in elderly patients.