The clinical observation of adefovir dipivoxil combined Fuzhenghuayu capsule treatment of chronic hepatitis B with liver fibrosis

Objective To explore the effect of Fuzhenghuayu capsule combined adefovir dipivoxil on liver fibrosis in chronic hepatitis B.Methods Seventy patients with chronic hepatitis B patients were randomly divided into combined treatment group(n=35,adefovir dipivoxil combined Fuzhenghuayu capsule) and the control group(n=35,Adefovir dipivoxil alone).Clinical efficacy was observed 48 weeks later.Results After 48 weeks,liver fibrosis indexs in the treatment group was significantly lower than control group(P0.05).Before treatment,spleen returned to normal thickness,portal vein diameter significantly reduced in treatment group,the differences were significant(P0.05).Conclusion Fuzhenghuayu capsule combind adefovir dipivoxil was effective on liver fibrosis in chronic hepatitis B.