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2011•The Journal of Medical Theory and PracticeRequires access

Clinical Efficacy of Carvedilol in Patients with Chronic Systolic Heart Failure

Wang Li-q

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Abstract

Objective:To evaluate the efficacy and safety of carvedilol in treatment of chronic heart failure(CHF).Methods:60 patients with CHF were randomly divided into treatment group(30 cases)and control group(30 cases).Two groups were treated with the routine medicine.Carvedilol was added to treatment group.After 6 months of treatment,two groups of improving heart function,LVEF,LVEDD and 6 minutes walk distance change was obserred.Symptoms and signs were recorded.Results:After treatment,The heart function and LVEF significantly increased.LVEDD and 6 minutes walk distance in treatment group reduced significantly.There was significantly difference between the two groups.Conclusion:Carvedilol is effective and safe in treating mild and moderate chronic congestive heart failure,which call improve the remodeling of left ventricle.

About this research paper

What this paper is about

Objective:To evaluate the efficacy and safety of carvedilol in treatment of chronic heart failure(CHF).Methods:60 patients with CHF were randomly divided into treatment group(30 cases)and control group(30 cases).Two groups were treated with the routine medicine.Carvedilol was added to treatment group.After 6 months of treatment,two groups of improving heart function,LVEF,LVEDD and 6 minutes walk distance change was obserred.Symptoms and signs were recorded.Results:After treatment,The heart function and LVEF significantly increased.LVEDD and 6 minutes walk distance in treatment group reduced significantly.There was significantly difference between the two groups.Conclusion:Carvedilol is effective and safe in treating mild and moderate chronic congestive heart failure,which call improve the remodeling of left ventricle.

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Available abstract

Objective:To evaluate the efficacy and safety of carvedilol in treatment of chronic heart failure(CHF).Methods:60 patients with CHF were randomly divided into treatment group(30 cases)and control group(30 cases).Two groups were treated with the routine medicine.Carvedilol was added to treatment group.After 6 months of treatment,two groups of improving heart function,LVEF,LVEDD and 6 minutes walk distance change was obserred.Symptoms and signs were recorded.Results:After treatment,The heart function and LVEF significantly increased.LVEDD and 6 minutes walk distance in treatment group reduced significantly.There was significantly difference between the two groups.Conclusion:Carvedilol is effective and safe in treating mild and moderate chronic congestive heart failure,which call improve the remodeling of left ventricle.

Key concepts: Carvedilol, Medicine, Heart failure, Ventricle, Ejection fraction, Cardiology, Internal medicine, Clinical efficacy

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