Antifungal resistance of deep part infection to commonly used drug

Objective:To investigate the distribution and antifungal resistance of deep part infection in Beijing Hospital from April 2003 to October 2003.Methods:Fungi were identified by CHROMagar and antifungal resistance were done by disk diffusion.Results:The major source of 285 isolated fungi were respiratory,urinary tract and digestive tract,including Candida albicans 133(46.7%),Candida glabrata 66(23.2%)and Candida tropicalis 54(18.9%).Antifungal resistance of 285 fungi were to Fluconazole 10.9%,Itraconazole 7.7% and Amphotericin B 0%,including Candida glabrata 26,Candida krusei 1,Candida guilliermondii 2 and Candida albicans 2 were resistant to Fluconazole;Candida krusei 1,Candida guilliermondii 2,Candida tropicalis 5,Candida glabrata 12 and Candida albicans 2 were resistant.Conclusion:Monitoring the antifungal resistance regularly is helpful to reasonable drug application.