Effects and security of insulin aspart therapy on type 2 diabetes

Objective To observe the clinical effect and security of insulin aspart 30 on type 2 diabetes.Methods Who sixty cases of poorly controlled type 2 diabetic patients on oral antidiabetic drug were randomly assigned into insulin aspart and Novolin 30R groups.They were treated with insulin aspart and Novolin 30R for 12 weeks,and then observed the change of glucose,HbA1c,fasting and postprandial C peptide,body mass,doses of insulin and the incidence rate of the hypoglycemia.Results Insulin aspart and Novolin 30R had effective control glucose(P0.05).There was no significant difference between two groups in fasting plasma glucose,but insulin aspart had more effective control glucose on 2 hours postprandial glucose of early and evening than Novolin 30R group.The incidence of hypoglycemia was lower in insulin aspart group(P0.05).Doses of insulin was lesser in insulin aspart group than another one.But it was no significant difference(P0.05) Conclusion Twice-daily subcutaneous insulin aspart injection could better control postprandial glucose and the incidence rate of hypoglycemia was lower.than in Novolin 30R group.