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2012•Zhongguo shiyan fangjixue zazhiRequires access

Optimization of Extract Technology of Corydalis decumbens by Orthogonal Experiment

Luo Xiao-jian

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Abstract

Objective:To optimize extraction process of Corydalis decumbens.Method:The content of bicuculline,protopine,tetrahydropalmatine,palmatine and yield of extract as indexes,optimization of extract technology by orthogonal experiment and correlation test and comprehensive balance method.Result:Optimum extraction condition was as follows:refluxing extracted 3 times with 11 times the amount of 70% ethanol by 2.5 h each time.Conclusion:This optimum technology was stable and feasible,it could keep effective components better.

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What this paper is about

Objective:To optimize extraction process of Corydalis decumbens.Method:The content of bicuculline,protopine,tetrahydropalmatine,palmatine and yield of extract as indexes,optimization of extract technology by orthogonal experiment and correlation test and comprehensive balance method.Result:Optimum extraction condition was as follows:refluxing extracted 3 times with 11 times the amount of 70% ethanol by 2.5 h each time.Conclusion:This optimum technology was stable and feasible,it could keep effective components better.

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Available abstract

Objective:To optimize extraction process of Corydalis decumbens.Method:The content of bicuculline,protopine,tetrahydropalmatine,palmatine and yield of extract as indexes,optimization of extract technology by orthogonal experiment and correlation test and comprehensive balance method.Result:Optimum extraction condition was as follows:refluxing extracted 3 times with 11 times the amount of 70% ethanol by 2.5 h each time.Conclusion:This optimum technology was stable and feasible,it could keep effective components better.

Key concepts: Protopine, Tetrahydropalmatine, Palmatine, Corydalis, Extraction (chemistry), Mathematics, Chromatography, Chemistry

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