1997•Unpublished venueRequires access

Naloxone in treating acute carbon monoxide poisoning

Bai Xiang

Abstract

AIM: To explore the effect of naloxone in treating carbon monoxide (CO) poisoning. METHODS: Twenty-one patients with CO poisoning (M 16, F 5, age 39±s 19 a) were treated with naloxone 1.2-1.6 mg in 5% glucose 20 mL, iv, qh, until the patients woke up besides conventional therapy; another 20 patients belong to control group (M 15, F 5, age 41±20 a) treated with preventing cerebral edema, remaining respiratory tract unobstruct, correcting the state of oxygen lacking etc. conventional therapy. RESULTS: The awaken times of middle and severe poisoning were 1.2±0.4 h, 2.6±0.6 h and 8.7±1.2 h, 13±4 h respectively (P0.01 or 0.05). CONCLUSION: Naloxone is an effective drug in the treatment of CO poisoning.

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Key concepts: (+)-Naloxone, Carbon monoxide poisoning, CO poisoning, Medicine, Anesthesia, Poison control, Internal medicine, Emergency medicine