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2006•Chinese journal of integrated traditional and Western medicineRequires access

Clinical and pathological analysis of 79 patients with occult hepatitis B

Zhou Da-ming

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Abstract

Objective:To explore the clinical and pathological characteristic of patients with occult hepatitis B.Methods:HBV DNA were detected by real time fluorescence quantitative PCR.Specimen of the liver biopsy were examined by immunochemistry.Results:HBV DNA were positive in the serum of 27 and in the specimen of the liver of 59 among the 79 patients,respectively;HBsAg and HBcAg in the specimen of the liver of 11 and 32 among the 79 patients were positive,respectively;77 patients with chronic hepatitis and 2 patients with early hepatocirrhosis among 79 patients were showed by pathological examination of the liver biopsy.Conclusion: The positive rate of HBV DNA in the specimen of the liver is higher than that of in the serum;There are different damage in the liver of the patients with occult hepatitis B.These patients needto be treated.

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Objective:To explore the clinical and pathological characteristic of patients with occult hepatitis B.Methods:HBV DNA were detected by real time fluorescence quantitative PCR.Specimen of the liver biopsy were examined by immunochemistry.Results:HBV DNA were positive in the serum of 27 and in the specimen of the liver of 59 among the 79 patients,respectively;HBsAg and HBcAg in the specimen of the liver of 11 and 32 among the 79 patients were positive,respectively;77 patients with chronic hepatitis and 2 patients with early hepatocirrhosis among 79 patients were showed by pathological examination of the liver biopsy.Conclusion: The positive rate of HBV DNA in the specimen of the liver is higher than that of in the serum;There are different damage in the liver of the patients with occult hepatitis B.These patients needto be treated.

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Available abstract

Objective:To explore the clinical and pathological characteristic of patients with occult hepatitis B.Methods:HBV DNA were detected by real time fluorescence quantitative PCR.Specimen of the liver biopsy were examined by immunochemistry.Results:HBV DNA were positive in the serum of 27 and in the specimen of the liver of 59 among the 79 patients,respectively;HBsAg and HBcAg in the specimen of the liver of 11 and 32 among the 79 patients were positive,respectively;77 patients with chronic hepatitis and 2 patients with early hepatocirrhosis among 79 patients were showed by pathological examination of the liver biopsy.Conclusion: The positive rate of HBV DNA in the specimen of the liver is higher than that of in the serum;There are different damage in the liver of the patients with occult hepatitis B.These patients needto be treated.

Key concepts: HBcAg, Medicine, Occult, HBsAg, Liver biopsy, Pathological, Gastroenterology, Hepatitis B

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