2009China Practical MedicineRequires access

Clinical observation of aztreonam in the treatment of patients with lower respiratory tract infection

Yin Cheng-fan

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Abstract

Objective To evaluate the efficacy and safety of aztreonam in the treatment of patients with lower respiratory tract infection.Methods A total of 346 cases were randomly divided into study group and control group(each group have 173 patients),study group(group A)were treated by aztreonam 2.0 g,control group(group B)were treated by cefepime 2.0 g,q12 h,all patients treated 7~14 days as a course.The clinical efficacy,the bacterial clearance rates and adverse drug reaction of 2 group were compared.Results The clinical efficacy rate of group A and B were 87.28%and 88.44%respectively,the bacterial clearance rates were 94.77%and 95.78%respectively,there were no statistical differences between 2 groups(P0.05).Conclusion Aztreonam is an effective and safe agent for treatment of patients with lower respiratory tract infection

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Objective To evaluate the efficacy and safety of aztreonam in the treatment of patients with lower respiratory tract infection.Methods A total of 346 cases were randomly divided into study group and control group(each group have 173 patients),study group(group A)were treated by aztreonam 2.0 g,control group(group B)were treated by cefepime 2.0 g,q12 h,all patients treated 7~14 days as a course.The clinical efficacy,the bacterial clearance rates and adverse drug reaction of 2 group were compared.Results The clinical efficacy rate of group A and B were 87.28%and 88.44%respectively,the bacterial clearance rates were 94.77%and 95.78%respectively,there were no statistical differences between 2 groups(P0.05).Conclusion Aztreonam is an effective and safe agent for treatment of patients with lower respiratory tract infection

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Available abstract

Objective To evaluate the efficacy and safety of aztreonam in the treatment of patients with lower respiratory tract infection.Methods A total of 346 cases were randomly divided into study group and control group(each group have 173 patients),study group(group A)were treated by aztreonam 2.0 g,control group(group B)were treated by cefepime 2.0 g,q12 h,all patients treated 7~14 days as a course.The clinical efficacy,the bacterial clearance rates and adverse drug reaction of 2 group were compared.Results The clinical efficacy rate of group A and B were 87.28%and 88.44%respectively,the bacterial clearance rates were 94.77%and 95.78%respectively,there were no statistical differences between 2 groups(P0.05).Conclusion Aztreonam is an effective and safe agent for treatment of patients with lower respiratory tract infection

Key concepts: Aztreonam, Medicine, Cefepime, Internal medicine, Respiratory tract infections, Respiratory tract, Clinical efficacy, Gastroenterology

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