Preparation of Amoxicillin Liposome and Its Quality Evaluation
Bo Yang
Abstract
Bo Yang
Abstract
The research was to prepare amoxicillin liposome by the film dispersion method,and to evaluate the quality of its mean diameter and entrapment rate.The pre-experiment confirmed the best process with the method of orthogonal design.Amoxicillin liposome were prepared under the condition of the optimal parameters,measuring the mean diameter and entrapment rate.The mean size of the liposome prepared was 114.6 nm,and the entrapment rate was 64.89%.The results showed that the method of amoxicillin liposome prepared by film dispersion was feasible,and was worth researching further.
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The research was to prepare amoxicillin liposome by the film dispersion method,and to evaluate the quality of its mean diameter and entrapment rate.The pre-experiment confirmed the best process with the method of orthogonal design.Amoxicillin liposome were prepared under the condition of the optimal parameters,measuring the mean diameter and entrapment rate.The mean size of the liposome prepared was 114.6 nm,and the entrapment rate was 64.89%.The results showed that the method of amoxicillin liposome prepared by film dispersion was feasible,and was worth researching further.
Key concepts: Liposome, Amoxicillin, Dispersion (optics), Entrapment, Chromatography, Materials science, Mathematics, Chemistry