2008•Journal of clinical and experimental medicineRequires access
The significance of detection of serum total bile acids in diagnosis of hepatobiliary diseases
Xiao Yan-qing
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Abstract
Objective To investigate the clinical significance of detection of serum total bile acids(TBA)in diagnosis of hepatobiliary diseases.Methods Serum level of TBA was determined by kinetic method in 140 patients(37 cases of acute hepatitis,45 cases of chronic hepatitis,20 cases of liver cirrhosis,25 cases of liver cancer and 13 cases of obstruction in bile ducts)and 62 healthy controls.Results The serum levels of TBA in above-mentioned patients were significantly higher than those of healthy controls(P0.01).The positive rates of raised level of TBA in patients with acute hepatitis,liver cirrhosis and liver cancer were over 80%.Conclusion Detection of serum level of TBA is a simple and practicable method for diagnosis of hepatobiliary diseases with important clinical significance.