2010•China Medical HeraldRequires access

Content determination of Chlorogenic acid in Lingqiao Jiedu Tablets by HPLC

Jing Luo

Abstract

Objective:To establish a method for the content determination of chlorogenic acid in Lingqiao Jiedu Tablets by HPLC. Methods:The Kromasil-C18(4.6 mm×200 mm,5 μm) column was used. The mobile phases consisted of methanol,water,acetic acid and triethylamine(18∶85∶1∶0.3) ,the flow rate was 1.0 ml/min and the detection wavelength was at 324 nm. Results:The linear range of Chlorogenic acid was at 17.22-172.20 μg/ml(r=0.999 8) ,the average recovery was 98.23% with a RSD of 0.71%(n=6) . Conclusion:The method is fast,reliable,accurate and can be used in the quality control of chlorogenic acid in Lingqiao Jiedu Tablets.

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Chlorogenic acid, Medicine, Triethylamine, Chromatography, High-performance liquid chromatography, Content determination, Acetic acid, Linear range