Clinical Observation on L-carnitine in the Treatment of Unstable Angina Pectoris

Objective:To investigate the clinical effects of L-carnitine in the treatment of unstable angina pectoris.Methods:Eighty-six patients with unstable angina pectoris were randomly divided into two groups, each group consisted of 43 cases.On the basis of conventional therapy, the patients from experimental group were administered L-carnitine, at the same time, those patients in control group were given GIK (glucose insulin-potasiun solution).Results:The total effective rates of relieved angina pectoris and improved ECG in treatment group were 93.02% and 76.74% respectively, nevertheless, that in control group were 65.12% and 48.84% respectively. There were significant difference between two group(P0.01).Conclusion:Adjunctive therapy with L-carnitine for treating unstable angina pectoris might be safe and effective way, L-carnitine could improve the energy metabolism of the ischemic myocardium.