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Application of Combined ANA Anti-ds-DNA and ENA to Diagnosis of SLE Patients

Lin Bao

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Abstract

Objective: To increase the sensitivity of detecting of SLE. Method Immunofluorescence assay for ANA,dot-immunobinding assay for Ads-DNA and immunoblotting for ENA were combined to examine in 50 serum samples from SLE patients. Result The positive rate of single test was 60% to 74%, but that of combined was 90%. Conclusion The three testings could be complementary to one another in diagnosis of SLE,resulting in an increase of the detection rate.

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What this paper is about

Objective: To increase the sensitivity of detecting of SLE. Method Immunofluorescence assay for ANA,dot-immunobinding assay for Ads-DNA and immunoblotting for ENA were combined to examine in 50 serum samples from SLE patients. Result The positive rate of single test was 60% to 74%, but that of combined was 90%. Conclusion The three testings could be complementary to one another in diagnosis of SLE,resulting in an increase of the detection rate.

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Available abstract

Objective: To increase the sensitivity of detecting of SLE. Method Immunofluorescence assay for ANA,dot-immunobinding assay for Ads-DNA and immunoblotting for ENA were combined to examine in 50 serum samples from SLE patients. Result The positive rate of single test was 60% to 74%, but that of combined was 90%. Conclusion The three testings could be complementary to one another in diagnosis of SLE,resulting in an increase of the detection rate.

Key concepts: Immunofluorescence, Indirect immunofluorescence, Molecular biology, DNA, Medicine, Immunology, Antibody, Internal medicine

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Application of Combined ANA Anti-ds-DNA and ENA to Diagnosis of SLE Patients — Research Paper | ScholarLens