Comparison of Liposoluble Constituents Extracted by SFE-CO_2 and Percolation from Salvia Miltiorrhiza

Objective To seek the optimal method and conditions for extracting liposoluble components from salvia miltiorrhiza,in order to develop comprehensive utilization of salvia miltiorrhiza. Methods The optimal extraction technology was chosen out by comparing and testing as contents of tanshinoneⅡA. Results The optimized conditions for SFE-CO2 extraction were as follows: pressure 35 MPa,100% ethanol as modifier,the temperature 40 ℃,the operation time 2 h,with the content reached 3.87 mg·g-1.The optimized conditions for Percolation were that 95%alcohol,16-fold solvent amount,flow rate 1.0 mL·min-1,20 meshes drug powder,with the content reached 3.28 mg·g-1. Conclusion SFE-CO2 is better than percolation with the higher extraction content,which shows that the comprehensive utilization of salvia miltiorrhiza could be feasible.