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2009•Journal of Chengdu Medical CollegeRequires access

Study on Extraction Process of Salvia Miltiorrhiza Bge.by SFE CO_2

WU Jin-wei

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Abstract

Objective To optimize the extraction process for Salvia miltiorrhiza Bge.by SFE CO2.Methods The orthogonal experiment was designed and the content of tanshinoneⅡA and salvianolic acid B were wed as index to determine the optimum technologic parameters.Results The optimum process was as follows:extracting pressure 30MPa,extracting temperature 40℃,extracting time 2h,separating pressure 5MPa.The extraction rate of tanshinoneⅡA and salvianolic acid B were 1.25 and 1.58 times higher than the trenditionerl method using alcohol.Conclusion With the extraction rate higher than the common method by alcohol,the optionnal process is stable,feasible and suitable for production.

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What this paper is about

Objective To optimize the extraction process for Salvia miltiorrhiza Bge.by SFE CO2.Methods The orthogonal experiment was designed and the content of tanshinoneⅡA and salvianolic acid B were wed as index to determine the optimum technologic parameters.Results The optimum process was as follows:extracting pressure 30MPa,extracting temperature 40℃,extracting time 2h,separating pressure 5MPa.The extraction rate of tanshinoneⅡA and salvianolic acid B were 1.25 and 1.58 times higher than the trenditionerl method using alcohol.Conclusion With the extraction rate higher than the common method by alcohol,the optionnal process is stable,feasible and suitable for production.

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Available abstract

Objective To optimize the extraction process for Salvia miltiorrhiza Bge.by SFE CO2.Methods The orthogonal experiment was designed and the content of tanshinoneⅡA and salvianolic acid B were wed as index to determine the optimum technologic parameters.Results The optimum process was as follows:extracting pressure 30MPa,extracting temperature 40℃,extracting time 2h,separating pressure 5MPa.The extraction rate of tanshinoneⅡA and salvianolic acid B were 1.25 and 1.58 times higher than the trenditionerl method using alcohol.Conclusion With the extraction rate higher than the common method by alcohol,the optionnal process is stable,feasible and suitable for production.

Key concepts: Salvia miltiorrhiza, Extraction (chemistry), Chromatography, Chemistry, Medicine, Traditional Chinese medicine, Pathology, Alternative medicine

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