Optimization of Extracting Technology of Effective Components from Salvia miltiorrhiza

Objective:To optimize extraction technology of liposoluble and water soluble ingredients from Salvia miltiorrhiza.Method:With the content of tanshinone ⅡA as index,effect of ethanol concentration,the amount of ethanol,extraction time and frequency on extraction technology of liposoluble ingredients from S.miltiorrhiza by single factor test and orthogonal test;With the content of salvianolic acid B as index,influence of water amount,extraction time and times on water-soluble ingredients from S.miltiorrhiza by L9(34) orthogonal test.Result:Optimal extraction technology of liposoluble ingredients was as following:extracted 3 times with 8 times the amount of 70% ethanol,30 min each time;Optimum extraction technology of water-soluble constituents from S.miltiorrhiza was as following:extracted 3 times with 5 times the amount of water,30 min each time.Conclusion:This optimized extraction technology was simple,stable and feasible,it was suitable for industrial production with a good prospect.