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2006•Unpublished venueRequires access

CT perfusion imaging of hepatocellular carcinoma

Qiu You-cai

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Abstract

Objective To study the changes of perfusion parameters in multislice CT perfusion imaging of hepatocellular carcinoma (HCC). Methods Dynamic CT scan with singe-location sequence was performed in 78 individuals including 70 patients with HCC and 8 control subjects. The liver perfusion parameters, such as blood flow (BF), blood volume (BV), mean transit time (MTT), permeability surface (PS) and hepatic arterial fraction (HAF), were calculated. Results Compared HCC with controls, HAF and BF in HCC group increased significantly, and MTT decreased significantly. BV and PS did not differ between the two groups. Conclusion The changes of hepatic perfusion parameters (HAF, BF and MTT) were of great value in evaluating the hemodynamics of HCC.

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What this paper is about

Objective To study the changes of perfusion parameters in multislice CT perfusion imaging of hepatocellular carcinoma (HCC). Methods Dynamic CT scan with singe-location sequence was performed in 78 individuals including 70 patients with HCC and 8 control subjects. The liver perfusion parameters, such as blood flow (BF), blood volume (BV), mean transit time (MTT), permeability surface (PS) and hepatic arterial fraction (HAF), were calculated. Results Compared HCC with controls, HAF and BF in HCC group increased significantly, and MTT decreased significantly. BV and PS did not differ between the two groups. Conclusion The changes of hepatic perfusion parameters (HAF, BF and MTT) were of great value in evaluating the hemodynamics of HCC.

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Available abstract

Objective To study the changes of perfusion parameters in multislice CT perfusion imaging of hepatocellular carcinoma (HCC). Methods Dynamic CT scan with singe-location sequence was performed in 78 individuals including 70 patients with HCC and 8 control subjects. The liver perfusion parameters, such as blood flow (BF), blood volume (BV), mean transit time (MTT), permeability surface (PS) and hepatic arterial fraction (HAF), were calculated. Results Compared HCC with controls, HAF and BF in HCC group increased significantly, and MTT decreased significantly. BV and PS did not differ between the two groups. Conclusion The changes of hepatic perfusion parameters (HAF, BF and MTT) were of great value in evaluating the hemodynamics of HCC.

Key concepts: Medicine, Hepatocellular carcinoma, Perfusion, Perfusion scanning, Mean transit time, Blood flow, Nuclear medicine, Blood volume

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