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2006•Journal of Medical ForumRequires access

Clinical Significance of Serum Cholesterol and Total Bile Acid in Patients with Hepatocirrhosis

Yue Ma

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Abstract

Objective To evaluate the clinical significance of serum cholesterol(CHO) and total bile acid(TBA) in patients with hepatocirrhosis.Methods The serum levels of CHO and TBA were prospectively studied in 85 patients with hepatocirrhosis and 68 healthy persons.Results Serum CHO level was significantly lower in cases with hepatocirrhosis than that of control group(P(0.05)),but serum TBA level significantly higher(P0.01).Serum CHO level was the lowest in Child-Pugh C grade and was significantly different between C grade and A grade as well as B grade(P(0.05)). Serum TBA level was significantly different among A,B and C grade,it increased with the liver function of Child-Pugh grade.Conclusion Serum TBA level can sensitively reflect the degree of hepatocirrhosis,the tests of TBA and CHO are helpful to confirming the state of patients.

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What this paper is about

Objective To evaluate the clinical significance of serum cholesterol(CHO) and total bile acid(TBA) in patients with hepatocirrhosis.Methods The serum levels of CHO and TBA were prospectively studied in 85 patients with hepatocirrhosis and 68 healthy persons.Results Serum CHO level was significantly lower in cases with hepatocirrhosis than that of control group(P(0.05)),but serum TBA level significantly higher(P0.01).Serum CHO level was the lowest in Child-Pugh C grade and was significantly different between C grade and A grade as well as B grade(P(0.05)). Serum TBA level was significantly different among A,B and C grade,it increased with the liver function of Child-Pugh grade.Conclusion Serum TBA level can sensitively reflect the degree of hepatocirrhosis,the tests of TBA and CHO are helpful to confirming the state of patients.

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Available abstract

Objective To evaluate the clinical significance of serum cholesterol(CHO) and total bile acid(TBA) in patients with hepatocirrhosis.Methods The serum levels of CHO and TBA were prospectively studied in 85 patients with hepatocirrhosis and 68 healthy persons.Results Serum CHO level was significantly lower in cases with hepatocirrhosis than that of control group(P(0.05)),but serum TBA level significantly higher(P0.01).Serum CHO level was the lowest in Child-Pugh C grade and was significantly different between C grade and A grade as well as B grade(P(0.05)). Serum TBA level was significantly different among A,B and C grade,it increased with the liver function of Child-Pugh grade.Conclusion Serum TBA level can sensitively reflect the degree of hepatocirrhosis,the tests of TBA and CHO are helpful to confirming the state of patients.

Key concepts: Internal medicine, Bile acid, Gastroenterology, Medicine, Clinical significance, Serum cholesterol, Liver function, Cholesterol

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