Clinical observation of applying mifepristone combined with misoprostol before curettage

Objective To evaluate clinical effect of mifepristone(taken orally) combined with misoprostol(laid in pudenda) before curettage for ending 11-15 weeks' pregnancy.Methods 200 women(11-15 weeks' pregnancy) randomly were divided into observation group,received the above-mentioned drugs and curettage;correspondingly 100 women(11-15 weeks' pregnancy) as control group,received artificial abortion under uterine nerve block anaesthesia.the following between the 2 groups such as dislatation of cervix,bleeding during operation,operative time,the syndrorne of artificial abortion and incomplete abortion complication were observed.Results There were marked differences(P0.05),the observation group obtained better effect than control group,the dilatation of cervix was better,the bleeding was less,the operative time was less,the syndrome of artifical obortion was less happening.Conclusion Mifepristone combined with misoprostols before curettage is safe and efficient treatment with mild side-effects for ending 11-15 weeks' pregnancy,it's worth clinically to spreading.