2010Chinese Journal of Diagnostic PathologyRequires access

Clinicapathologic features of hemangiopericytoma/solitary fibrous tumor of breast

F Chen

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Abstract

Objective To investigate the pathologic characteristics of hemangiopericytoma/solitary fibrous tumor (HPC/ SFT) in the breast,and its diagnosis and differential diagnosis from other tumors. Methods One case of HPC/SFT was observed with pathologic examination and the related literature was briefly reviewed. Results Histologically,this tumour showed an abundant vascular pattern forming a continuous ramifying network; the tumor cells had radiational or suffusive array around vessels,and appeared roundish,oval or fusiform with indistinct cell ambit. The tumor cells expressed vimentin,CD34,CD99 and bcl-2. Conclusion HPC/SFT is a rare soft tissue tumour in the breast,with good prognosis. So its correct diagnosis and differential diagnosis can be made with careful analyses of the histopathological and immunohistochemical data.

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What this paper is about

Objective To investigate the pathologic characteristics of hemangiopericytoma/solitary fibrous tumor (HPC/ SFT) in the breast,and its diagnosis and differential diagnosis from other tumors. Methods One case of HPC/SFT was observed with pathologic examination and the related literature was briefly reviewed. Results Histologically,this tumour showed an abundant vascular pattern forming a continuous ramifying network; the tumor cells had radiational or suffusive array around vessels,and appeared roundish,oval or fusiform with indistinct cell ambit. The tumor cells expressed vimentin,CD34,CD99 and bcl-2. Conclusion HPC/SFT is a rare soft tissue tumour in the breast,with good prognosis. So its correct diagnosis and differential diagnosis can be made with careful analyses of the histopathological and immunohistochemical data.

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Available abstract

Objective To investigate the pathologic characteristics of hemangiopericytoma/solitary fibrous tumor (HPC/ SFT) in the breast,and its diagnosis and differential diagnosis from other tumors. Methods One case of HPC/SFT was observed with pathologic examination and the related literature was briefly reviewed. Results Histologically,this tumour showed an abundant vascular pattern forming a continuous ramifying network; the tumor cells had radiational or suffusive array around vessels,and appeared roundish,oval or fusiform with indistinct cell ambit. The tumor cells expressed vimentin,CD34,CD99 and bcl-2. Conclusion HPC/SFT is a rare soft tissue tumour in the breast,with good prognosis. So its correct diagnosis and differential diagnosis can be made with careful analyses of the histopathological and immunohistochemical data.

Key concepts: Hemangiopericytoma, Solitary fibrous tumor, CD99, Medicine, Vimentin, Pathology, Differential diagnosis, CD34

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