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Solitary fibrous tumors: 3 case reports and literature review

Wenbo Zhang

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Abstract

[Objective] To investigate the clinicopathologic characteristics of solitary fibrous tumors.[Methods] The clinical features,pathologic patterns and immunophenotype were analysed for three cases of SFTs.[Results] Histologically,SFT was composed of bland spindle cell,typically arranged in haemangiopericytoma-like pattern.Positive immunoreactivity for vimentin,CD34 and bcl-2,negative for Cytokeratin(Pan),SMA,CD117 and S-100.[Conclusions] SFT is a rare tumor,differential diagnosis should be made with mesothelioma,hemangiopericytoma neurofibroma and others.

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[Objective] To investigate the clinicopathologic characteristics of solitary fibrous tumors.[Methods] The clinical features,pathologic patterns and immunophenotype were analysed for three cases of SFTs.[Results] Histologically,SFT was composed of bland spindle cell,typically arranged in haemangiopericytoma-like pattern.Positive immunoreactivity for vimentin,CD34 and bcl-2,negative for Cytokeratin(Pan),SMA,CD117 and S-100.[Conclusions] SFT is a rare tumor,differential diagnosis should be made with mesothelioma,hemangiopericytoma neurofibroma and others.

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Available abstract

[Objective] To investigate the clinicopathologic characteristics of solitary fibrous tumors.[Methods] The clinical features,pathologic patterns and immunophenotype were analysed for three cases of SFTs.[Results] Histologically,SFT was composed of bland spindle cell,typically arranged in haemangiopericytoma-like pattern.Positive immunoreactivity for vimentin,CD34 and bcl-2,negative for Cytokeratin(Pan),SMA,CD117 and S-100.[Conclusions] SFT is a rare tumor,differential diagnosis should be made with mesothelioma,hemangiopericytoma neurofibroma and others.

Key concepts: Solitary fibrous tumor, Hemangiopericytoma, Vimentin, CD34, CD117, Cytokeratin, Pathology, Immunophenotyping

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