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Extraction and purification of chlorogenic acid from Eucommia ulmoide oliver leave

Junhai Liu, Qiu Ai-yong

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Abstract

The chlorogenic acid is an important bioactivity material.The process of extracting chlorogenic acid from Eucommia ulmoides oliver leaves,with aqueous acetone as extraction solvent,was studied. The optimum extraction conditions were as following: temperature 65℃,40% aqueous acetone,a ratio of material to solvent 1∶12,extraction duration 3 h.After extracted under the optimum conditions and purified with polyamide column chromatography,the yield and purity of chlorogenic acid were 27.4% and 77.04% ,respectively.It is expected to provide reference for other material to extract chlorogenic acid.

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What this paper is about

The chlorogenic acid is an important bioactivity material.The process of extracting chlorogenic acid from Eucommia ulmoides oliver leaves,with aqueous acetone as extraction solvent,was studied. The optimum extraction conditions were as following: temperature 65℃,40% aqueous acetone,a ratio of material to solvent 1∶12,extraction duration 3 h.After extracted under the optimum conditions and purified with polyamide column chromatography,the yield and purity of chlorogenic acid were 27.4% and 77.04% ,respectively.It is expected to provide reference for other material to extract chlorogenic acid.

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Available abstract

The chlorogenic acid is an important bioactivity material.The process of extracting chlorogenic acid from Eucommia ulmoides oliver leaves,with aqueous acetone as extraction solvent,was studied. The optimum extraction conditions were as following: temperature 65℃,40% aqueous acetone,a ratio of material to solvent 1∶12,extraction duration 3 h.After extracted under the optimum conditions and purified with polyamide column chromatography,the yield and purity of chlorogenic acid were 27.4% and 77.04% ,respectively.It is expected to provide reference for other material to extract chlorogenic acid.

Key concepts: Chlorogenic acid, Eucommia ulmoides, Extraction (chemistry), Chromatography, Chemistry, Acetone, Aqueous solution, Polyamide

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